Unilateral lower extremity lymphedema as a first symptom of primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT)

Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), is a rare and aggressive variant of extranodal lymphoma. We report the case 64-year-old woman with unilateral lymphedema lower limb as first only symptom PCDLBCL-LT for six months. Violaceous nodules were second they progressively developed on edematous calf. Initially, diagnosed warty overgrowths, which are common skin changes in course chronic lymphedema. The lack improvement violaceous after compression therapy prompted to perform biopsy. Histopathological evaluation revealed presence PCDLBCL-LT. In this article, we want highlight challenges making diagnosis PCDLBCL- -LT. To our knowledge, no other study has reported an initial